2007年 論文発表

分子遺伝学的検査

Development of a novel nano-Invader DNA chip system

◆Journal of biochemical and biophysical methods 70 : 787-795 (2007)
Sachio Nomura1, Masatoshi Kondo2, Makoto Nagano1, Kana Matsui1, Toru Egashira1
  1. Division of Advanced Medical Technology and Development, BML Inc.
  2. Department of Molecular and Cell Biology, University of Connecticut, Connecticut, USA.

Polymorphisms of apolipoprotein E and methylenetetrahydrofolate reductase in the Japanese population

◆Journal of Atherosclerosis and Thrombosis 14:167-171 (2007)
Hidenori Arai1, Akira Yamamoto2, Yuji Matsuzawa3, Yasushi Saito4, Nobuhiro Yamada5, Shinichi Oikawa6, Hiroshi Mabuchi7, Tamio Teramoto8, Jun Sasaki9, Noriaki Nakaya10, Hiroshige Itakura11, Yuichi Ishikawa12, Yasuyoshi Ouchi13, Hiroshi Horibe14, Toru Egashira15, Hiroaki Hattori15, Toru Kita16
  1. Department of Geriaeric Medicine, Kyoto University Graduate School of Medicine, Japan.
  2. National Cardiovascular Center, Japan.
  3. Sumitomo Hospital, Japan.
  4. Department of Clinical Cell Biorogy and Medicine, Chiba University, Japan.
  5. Department of Internal Medicine, University of Tsukuba, Japan.
  6. Department of Internal Medicine,Noppon Medical School, Japan.
  7. Department of Laboratory Science, Kanazawa University, Japan.
  8. Department of Internal Medicine, Teikyo University, Japan.
  9. International University of Health and Welfare, Japan.
  10. Fussa Hospital, Japan.
  11. Ibaraki Christian University, Japan.
  12. Faculty of Health Sciences, Kobe University of Tokyo, Japan.
  13. Department of Geriatric Medicine, University of Tokyo, Japan.
  14. Keisen Clinic, Japan.
  15. Department of Advanced Techonology and Development, BML, Inc., Japan.
  16. Department of Cardiovescular Medicine, Kyoto University Graduate School of Medicine, Japan.

新たに見出されたlipoprotein lipase欠損症(Gly188Arg)によるカイロミクロン血症の1例

◆The Lipid 18 : 190-197 (2007)
高田耕基1, 豊田康嗣1, 平岡明人1, 光波直也1, 長野誠2, 服部浩明2
  1. 広島鉄道病院循環器内科
  2. 株式会社ビー・エム・エル

Evaluation the Invader Assay with the BACTEC MGIT 960 System for Prompt Isolation and Identification of Mycobacteria from Clinical Specimens

◆Journal of Clinical Microbiology 45 : 3316-3322 (2007)
Ichimuara S1, Nagano M1, Ito N1, Shimojima M1, Egashira T1, Miyamoto C1, Ohkusu K2, Ezaki T2
  1. Department of Microbiorogy
  2. Division of Advanced Technology, BML, Inc., Saitama , Japan.
  3. Department Microbiorogy, Regeneration and Advanced Medical Science, Gifu University Graduate School of Medicine, Gifu, Japan.

Molecular Characterization and Diagnosis of QoI Resistance in Cucumber and Eggplant Fungal Pathogens

◆Phytopathology 11 : 1458-1466 (2007)
H.Ishii1, K.Yano2, H.Date3, A.Furuta3, Y.Sagehashi5, T.Yamaguchi5, T.Sugiyama1, K.Nishimura1, W.Hasama6
  1. National Institute for Agro-Environmental Sciences, Ibaraki Japan.
  2. Kochi Agricultural Research Center, Kochi, Japan.
  3. Agricultural Experiment Station, Okayama Prefecttural General Agriculture Center, Okayama, Japan.
  4. Saga Prefectural Agricultural Research Center, Agricultural Research Center, Saga, Japan.
  5. BML, Saitama, Japan.
  6. Oita Prefectural Agricultural Research Center, Oita, Japan.

Invader法を用いた抗酸菌同定法

◆Medical Technology 35 : 6-8 (2007)
長野誠1, 市村禎宏2, 伊藤伸子1, 霜島正浩2, 江頭徹1
  1. 株式会社ビー・エム・エル臨床ゲノム開発部
  2. 株式会社ビー・エム・エル安全性試験部

Application of Deafness Diagnostic Screening Panel Based on Deafness Mutation/Gene Database Using Invader Assay

◆Genetic Testing 11: 333-340 (2007)
Satoko Abe1, Toshikazu Yamaguchi1, Shin-Ichi Usami2
  1. Division of Advanced Technology and Development, BML, Inc., Saitama, Japan.
  2. Department of Otorhinolaryngologi, Shinsyu University School of Medicine, Nagano, Japan.

Effects of CO2 Laser Treatment Combined with Scaling and Root Planing on Periodontal Pockets in Chronic Periodontitis Patients

◆日本歯周病学会会誌 49 : 130-138 (2007)
Kaku Watanabe1, Masashi Murata1, Taichi Nagamori1, Toshikazu Yamaguchi2, Hiromasa Yoshie1
  1. Division of Periodontology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Japan.
  2. Division of Clinical Development, R&D Center, BML, Inc., Japan.

インベーダー法によるミトコンドリア遺伝子1555変異 ヘテロプラスミー定量測定法の開発

◆Otology Japan 17 : 691-696 (2007)
清水恒典1, 阿部聡子1, 2, 山口敏和1, 呂旭原3, 宇佐美真一3
  1. 株式会社ビー・エム・エル臨床ゲノム部
  2. あべ耳鼻咽喉科アレルギー科
  3. 信州大学医学部耳鼻咽喉科学教室

Multiplex PCR/Liquid Chromatography Assay for Screening of Subtelomeric Rearrangements

◆Genetic Testing 11:241-248 (2007)
TORU UDAKA1, ISSEI IMOTO2, YOSHINORI AIZU2, 3, CHIHARU TORII1, KOSUKE IZUMI1, RIKA KOSAKI4, TAKAO TAKAHASHI1, SHIN HAYASHI2, JOHJI INAZAWA2, 5, KENJIRO KOSAKI1
  1. Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan.
  2. Department of Molecular Cytogenetics, Medical Research Institute and Graduate School of Biomedical Science, Tokyo Medical and Dental University, Tokyo, Japan.
  3. Research and Development Center, BML, Kawagoe, Japan.
  4. Department of Clinical Genetics and Molecular Medicine, National Children's Mediacal Center, Tokyo, Japan.
  5. Hard Tissue Genome Research Center, Tokyo Medical and Dental University, Tokyo, Japan.

生化学的検査

Plasma apoAV levels are markedly elevated in severe hypertriglyceridemia and positively correlated with the APOA5 S19W polymorphism

◆Atherosclerosis 193 : 129-134 (2007)
Peter Henneman1, Frank G. Schaap2, Louis M. Havekes3, 4, 5, Patrick C.N. Rensen3, 4, Rune R. Frants1, Arie van Tol6, Hiroaki Hattori7, August H.M. Smelt3, Ko Williems van Dijk1, 3
  1. Department of Human Genetics, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands.
  2. AMC Lever Centre, Meibergdreef 69-71, 1105 BK, Amsterdam, The Netherlands.
  3. Department of General Internal Medicine, Endocrinology and Metabolism, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands.
  4. Department of Cardiology, Leiden University Medical Center, P.O. Box 2215, 2301 CE Leiden, The Netherlands.
  5. TNO-Quality of Life, Department of Biomedical Research , Gaubius Laboratory, P.O. Box 2215, 2301 CE Leiden, The Netherlands.
  6. Department of Biochemistry, Erasmus Medical Center, Rotterdam, The Netherlands.
  7. Department of Advenced Medical Technology and Development, BML, Inc., Saitama, Japan.

血液中および尿中カドミウムの施設間クロスチェック

◆労働衛生管理 18 : 43-44 (2007)
奈良部安, 津田聡一郎
株式会社ビー・エム・エル

内分泌学的検査

Serum resistin level is associated with insulin sensitivity in Japanese patients with type 2 diabetes mellitus

◆Metabolism 56 : 693-698 (2007) 
Yoshiharu Tokuyama1, Haruhiko Osawa2, Toshiharu Ishizuka1, Hiroshi Onuma2, Kana Matsui3, Toru Egashira3, Hideichi Makino2, Azuma Kanatsuka1
  1. betes Center, Chiba Central Medical Center, Chiba, Japan.
  2. Department of Laboratory Medicine, Ehime University School of Medicine, Ehime, Japan.
  3. Division of Clinical Development, R&D Center, BML Inc., Saitama, Japan

免疫学的検査

Serum granulysin and its clinical significance

◆Res Adv Hematology 2 : 1-6 (2007)   
Masayuki Nagasawa1, Kazuyuki Ogawa2, Kinya Nagata2, Masataka Nakamura3
  1. Department of Pediatrics.
  2. B.M.L R&D Center, Saitama, Japan.
  3. Human Gene Sciences Center, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.

Serum granulysin level as a novel prognostic marker in patients with gastric carcinoma

◆Journal of Gastroenterology and Hepatology 22 : 1322-1327 (2007)
Susumu Saigusa1, Takashi Ichikura1, Hironori Tsujimoto1, Hidekazu Sugasawa1, Takashi Majima1, Nobuaki Kawarabayashi1, Kentaro Chochi1, Satoshi Ono1, Manabu Kinoshita2, Suhji Seki2, Kazuyuki Ogawa3, Hidetaka Mochizuki1
  1. First Department of Surgery, National Defense Medical College, Japan.
  2. Division of Basic Traumatology, Research Institute, National Defense Medical College. Japan.
  3. Department of Microbiology, National Defense Medical College. Japan.
  4. R&D Center, BML, Kawagoe, Saitama, Japan.

Serum Granulysin is Elevated in Patients with Hemophagocytic Lymphohistiocytosis

◆International Journal of Hematology 86:470-473 (2007)
Masayuki Nagasawa1, Kazuyuki Ogawa2, Shinsaku Imasyuku3, Syuki Mizutani1
  1. Department of Pediatrics and Development Biology, Postgraduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
  2. B.M.L. R&D Center and Laboratory Headquarters, Saitama, Japan.
  3. Department of Pediatrics, Kyoto Prefectural University, Kyoto, Japan.

微生物学的検査

各都道府県から分離された新鮮臨床分離株80万株の各種抗菌薬に対する感受性検査成績(第5報:2006年4月~2007年3月)

◆診療と新薬 44 : 787-843 (2007)
霜島正浩
株式会社ビー・エム・エル細菌学課

透析液清浄化 ISO基準はクリアできるか 膜濾過法における透析液細菌数測定法

◆腎と透析 63(別冊 HDF療法'07): 16-19 (2007)
霜島正浩
株式会社ビー・エム・エル細菌学課

透析液(透析用水)における微生物検査について(現状調査を含む)

◆生物試料分析 30 : 134-143 (2007)
霜島正浩
株式会社ビー・エム・エル細菌学課

Epstein-BarrウイルスIgM抗体の検出状況、1999-2006年 1臨床検査会社での集計結果

◆感染症学雑誌 81 : 707-713 (2007)  
増井幸雄1, 板橋愛宜1, 石井暁1, 伴文彦1, 井上栄2
  1. 株式会社ビー・エム・エル
  2. 大妻女子大学家政学部

急性ウイルス感染症のIgM抗体検出状況、1995-2004年 一臨床検査会社での集計結果

◆感染症学雑誌 81 : 426-434 (2007)
伴文彦1, 板橋愛宜1, 増井幸雄1, 井上栄2
  1. 株式会社ビー・エム・エル
  2. 大妻女子大学家政学部

Helicobacter pyloriに対するE-testの検討

◆医学検査 56 : 1132-1134 (2007) 
飯沼克浩, 坪井五三美
株式会社ビー・エム・エル総合研究所

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