2009年 論文発表

分子遺伝学的検査

第三世代の臨床歯周病細菌検査 -Porphyromonas gingivailsの遺伝子型検査の臨床応用;fimA type-

◆歯界展望 113: 311-320 (2009)
吉野敏明1, 田中真喜1, 関根聡2, 河村勝美3
  1. 吉野歯科診療所歯周病プラントセンター
  2. 関根歯科医院
  3. 株式会社ビ-・エム・エル臨床ゲノム部ゲノム開発課

造血器腫瘍の遺伝子診断における検査検体の取り扱い

◆日本検査血液学会雑誌 10: 99-105 (2009)
山口敏和
株式会社ビー・エム・エル臨床ゲノム部

マルチプレックス-リアルタイムPCRを用いた感染性胃腸炎ウイルスの網羅的検出法の開発

◆臨床と微生物 36: 251-256 (2009)
田所健一1, 山口敏和1, 篠原美千代2
  1. 株式会社ビー・エム・エル臨床ゲノム部
  2. 埼玉県衛生研究所

Serial monitoring of T315I BCR-ABL mutation by Invader assay combined with RT-PCR

◆Int J Hematol 89: 482-488 (2009)
Masahide Yamamoto1, Kazuhiko Kakihana1, Kazuteru Ohashi1, Toshikazu Yamaguchi2, Kenichi Tadokoro2, Hideki Akiyama1, Hisashi Sakamaki1
  1. Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
  2. Development of Clinical Genomics, BML, Saitama, Japan

Quantitation of viral load by real-time PCR-monitoring lnvader reaction

◆Journal of Virological Methods 155: 182-186 (2009)
Kenichi Tadokoro1, Toshikazu Yamaguchi1, Toru Egashira1, Takashi Hara2
  1. Development of Clinical Genomics, BML, Inc, Saitama, 350-1101, Japan
  2. Ibaraki prefectural institute of Pubulic Heaith, Ibaraki 310-0852, Japan

生化学的検査

ペプシノーゲン測定用ラテックス試薬の基礎的検討

◆医学検査 58: 1242-1247 (2009)
飯沼克弘, 武内剛, 八塚信明, 坪井五三美
株式会社ビー・エム・エル総合研究所試薬部

尿中ミオイノシトール測定用試薬の基礎的検討

◆医学検査 59: 1337-1340 (2009)
飯沼克弘, 武内剛, 坪井五三美
株式会社ビー・エム・エル総合研究所試薬部

免疫学的検査

塩基球CD203c発現定量による新しいアレルギー検査の可能性

◆Medical Science Digest 35: 33-36 (2009)
篠田牧人1, 平井博之2, 橋口明彦1, 野間芳弘1, 永田欽也2, 長尾みづほ3, 徳田玲子3, 藤澤隆夫3, 灰田美知子4
  1. 株式会社ビー・エム・エル特殊技術部
  2. 株式会社ビー・エム・エル先端医療開発部
  3. 国立病院機構三重病院 臨床研究部
  4. 半蔵門病院アレルギー呼吸器内科

Identification of mesenchmal stem xell (MSC)-transcription factors by microarray and knockdown analyses, and signature molecule-marked MSC in bone marrow by immunohistochemistry

◆Genes to Cells 14: 407-242 (2009)
Hiroshi Kudo1, Masakazu Shimizu1, Yuji Taya2, Takeshi Kawamoto1, Masahiko Michida3, Emi Kaneko1, Akira Igarashi1, Masahiro Nishimura4, Kazumi Segoshi4, Yoshihito Shimazu2, Koichiro Tsuji5, Takaaki Aoba2, Yukiko Kato1
  1. Department of Dental and Medical Biochemistry, Graduate School of Biomedecal Sciences, hiroshima University, Hiroshima Japan
  2. Department of Pathology, Nippon Denatal University, Tokyo Japan
  3. Department of Orthodontics and Craniofacial Developmental Biology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
  4. Prosthetic Dentistry, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan

Functional Protein Delivery into Neurons Using Polymeric Nanoparticles

◆THE JOURNAL OF BIOLOGICAL CHEMISTRY 284: 6972-6981 (2009)
Linda Hasadsri1, Jorg Kreuter2, Hiroaki Hattori3, Tadao Iwasaki3, Julia M. George4
  1. Department of Cell and Developmental Biology and College of Medicine (Medical  ScholarsProgram), Unoversity of Illinois Urbana-Champain, Urbana, Illinois 6180
  2. Institut fur Pharmazeutische Technologie, Biozentrum, Johann Wolfgang Goethe Universitat, Franlfult D-60439, Germany
  3. Department of Advanced Medical Technology and Development, BML, Inc.
  4. Department of Molecular and Integrative Physiology, University of Illinois Urbana-Champaign

Ataxia with vitamin E deficiency with a mutation in a phospholipid transfer protein gene

◆J Neurol 256: 1180-1181 (2009)
Satoshi Kono1, Akiko Otsuji1, Hiroaki Hattori2, Kentaro Shirakawa1, Hitoshi Suzuki1, Hiroaki Miyajima1
  1. First Department of Medicine, Hamamatsu University School of Medicine
  2. Department of Advanced Medical Technology and Development, BML, Inc, kawagoe, Japan

Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport

◆nature structural & molecular biology 16: 1026-1035 (2009)
Hidetaka Kosako1, 2, Nozomi Yamaguchi1, 3, Chizuru Aranami4, Masato Ushiyama1, 5, Shingo Kose6, Naoko Imamoto6, Hisaki Taniguchi2, Eisuke Nishida7, Seisuke Hattori1, 4
  1. Division of Cellular Proteomics (BML), Institute of Medical Science, The University of Tokyo, Tokyo, Japan
  2. Division of Disease Proteomics, Institute for Enzyme Research, The University of Tokushima, Tokushima, Japan
  3. R&D Center, BML, Inc., Saitama, Japan
  4. Department of Biochemistry, School of Pharmaceutical Sciences, Kitasato University, Tokyo,Japan
  5. GE Healthcare Bio-Sciences KK, Tokyo, Japan
  6. Cellulasr Dynamics Labpratory, Advanced Science Institute, RIKEN, Saitama,Japan
  7. Department of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan

Increased expression and cellular localization of lipocalin-type prostaglandin D synthase in Helicobacter pylori-inducsd gastritis

◆Journal of Pathology J Pathol 219: 417-426 (2009)
Ryota Hokari1, Nanae Nagata2, Chie Kurihara1, Chikako Watanabe1, Shunsuke Komoto1, Yoshikiyo Okada1, Atsushi Kawaguchi1, Shigeaki Nagano1, Toshifumi Hibi3, Kinya Nagata4, Yoshihiro Urabe2, Soichiro Miura1
  1. Department of Internal Medicine, National Defense Medical College, Saitama, Japan
  2. Department of Molecular Behavioral Biology, Osaka Bioscience Institute, Osaka, Japan
  3. Department of Internal Medicine, School of medicine, Keio University, Tokyo, Japan
  4. BML Research and Development, Saitama, Japan

A novel APOA5 splicing mutation IVS2+1g> a in a Japanese chylomicronemia patient

◆Atherosclerosis 207: 24-25 (2009)
Minoru Okubo1, 2, Mitsuaki Ishihara3, Tadao Iwasaki3, Tetsu Ebara1, Yoshiko Aoyama1, Toshio Murase1, Hiroaki Hattori3
  1. Okinawa Memorial Institute for Medical Research
  2. Department of Endocrinology and Metabolism, Toranomon Hospital
  3. Advanced Technology and Development Division, BML, Inc.

Significance of Urinary Glucaric Acid Measurement and Its Application to Paclitaxel Therapy

◆癌と化学療法 36: 1857-1861 (2009)
Shigefumi Morimoto2, Toshiski Koda2, Tomoki Suidzu2, Ryunosuke Uranishi3, Yosihara Shono4, Isao Akiyama5, Kumiyo Shimizu6, Yoshikazu Fujita2, Kenji Hasegawa1, Katsuyoshi Tabuse4
  1. Dept. of Pharmacy, Osaka Minami Medical Centrs, National Hospital Organization
  2. Clinical Chemistry Laboratory, Osaka University of Pharmaceutical Sciences
  3. Dept. of Neurosurgery, Osaka Minami Medical Centrs, National Hospital Organization
  4. Dept. of Surgery, Osaka Minami Medical Centrs, National Hospital Organization
  5. BML, INC. General Laboratory Environmental Test Section
  6. Dept. of Pharmacy, Yodogawa Christian Hospital

Biomarkers for Allergen Immunotherapy in Cedar Pollinosis

◆Allergol Int. 58:163-170 (2009)
Takao Fujisawa1, Mizuho Nagao1, Yukiko Hiraguchi1, Koa Hosoki1, Reiko Tokuda1, Satoko Usui2, Sawako Masuda2, Makito Shinoda3, Akihiko Hashiguchi3 and Masao Yamaguchi4
  1. Institute for Clinical Research
  2. Department of Otorhinolaryngology, Mie National Hospital, Mie
  3. Department of Special Analysis, BML, Inc., Saitama
  4. Department of Allergy and Rheumatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan

その他

手袋で試薬のフタに触れるべからず!-ラテックス手袋の粉が検査値に及ぼす影響

◆Medical Technology 37: 589-590 (2009)
鷹取明美1, 2, 北舘克憲1, 2, 矢澤直行1, 木村聡3
  1. 昭和大学横浜市北部病院
  2. 株式会社ビー・エム・エル
  3. 昭和大学横浜市北部病院臨床検査科

使い捨て手袋が生化学項目の測定に及ぼす影響

◆検査と技術 37: 769-771 (2009)
鷹取明美1, 2, 北舘克憲1,2, 矢澤直行1, 木村聡3
  1. 昭和大学横浜市北部病院
  2. 株式会社ビー・エム・エル
  3. 昭和大学横浜市北部病院臨床検査

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